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Logic & science2 MINBrief fileEstablished evidence

Causal Confounding

Two groups may differ before the supposed treatment in a way that also changes the outcome.

01 / SUMMARY

In short

Confounding occurs when a common cause, or equivalent structure, mixes the exposure's effect with baseline differences. Adjustment can help only when the needed variables are properly identified and measured.

03 / SCENE

In the wild

People taking a supplement also exercise more; comparing health without handling exercise mixes the two processes.

04 / LIMIT

The limit

Adding every available variable to a regression can create bias when one is a mediator or collider.

FINAL NOTE

What remains

Choose adjustments from a causal model, not an automatic covariate list.